The Ministry of Entrepreneurship, Microenterprise and Small Business () is a cabinet-level federal ministry in Brazil. It is an institution previously created in 2013 as the Secretariat for Micro and Small Enterprises (), a cabinet-level secretariat under the responsibility of the Presidency of the Republic from 2013 to 2015. It was dissolved after a ministry shuffle in October 2015. Since then, it became part of the Secretariat of Government of the Presidency, without a ministry status. On 1 January 2019, its functions were merged into the recently created Ministry of the Economy. On 13 September 2023, it was recreated as a ministry.