Mill Creek is a stream in northern Dallas County in the Ozarks of southwest Missouri. It is a tributary of the Niangua River.
The stream headwaters are at and the confluence with the Niangua is at . The stream source area lies east of Missouri Route 73 and it flows east passing north of the Lead Mine Conservation Area. It flows parallel to Missouri Route E and past the community of Celt prior to its confluence with the Niangua River.
Mill Creek was named on account of the watermills along its course.