Middle Mesa is a census-designated place (CDP) in San Juan County, New Mexico, United States. It was first listed as a CDP following the 2010 census, replacing the Young Place CDP. As of the 2020 census, Middle Mesa had a population of 200.
The CDP is in the extreme northeast corner of the county, bordered to the north by La Plata and Archuleta counties in Colorado. It is to the west of Navajo Reservoir on the San Juan River. It is by as the crow flies and by road northeast of Aztec, the San Juan county seat, and southwest of Arboles, Colorado.