Mezzane di Sotto is a comune (municipality) in the Province of Verona in the Italian region Veneto, located about west of Venice and about northeast of Verona. As of 31 December 2004, it had a population of 1,949 and an area of .
Mezzane di Sotto borders the following municipalities: Illasi, Lavagno, San Martino Buon Albergo, Tregnago, and Verona.