Mezhdurechye () is a rural locality (a settlement) in Vtorokamensky Selsoviet, Loktevsky District, Altai Krai, Russia. The population was 86 as of 2013. There is 1 street.
Mezhdurechye is located on the Kamenka River, 32 km northeast of Gornyak (the district's administrative centre) by road. Gilyovo is the nearest rural locality.