San Antonio Abad is a station on Line 2 of the Mexico City Metro system. It is located in the Colonia Tránsito and Colonia Obrera neighborhoods of the Cuauhtémoc borough of Mexico City, to the south of the city centre, in the median of Calzada San Antonio Abad.
The station logo depicts Saint Anthony the Great, after the monastery dedicated to him that was established in the area after the Spanish conquest of Tenochtitlán. The section of the avenue on which the station sits is also called after him, but due south it later becomes the Calzada de Tlalpan.
Metro San Antonio Abad is the first street-level station on the southern section of Line 2. The station opened on 1 August 1970.