The Metro Manila Film Festival Award for Best Supporting Actor is an award presented annually by the Metropolitan Manila Development Authority (MMDA). It was first awarded at the 1st Metro Manila Film Festival ceremony, held in 1975; Vic Silayan received the award for his role in Diligan Mo ng Hamog ang Uhaw na Lupa and it is given in honor of an actor who has delivered an outstanding performance in a supporting role while working within the film industry. Currently, nominees and winners are determined by Executive Committees, headed by the Metropolitan Manila Development Authority Chairman and key members of the film industry.
Throughout the history of Metro Manila Film Festival (MMFF), there have been actors who received multiple Awards for Best Supporting Actor. As of 2021 (47th MMFF), 7 actors have received two or more Best Supporting Actor awards.