In Greek and Roman mythology, Menephron () is the name of an Arcadian man notable for his tale surrounding incest. He is only referenced briefly in the works of Roman authors Ovid and Hyginus.
In Ovid's Metamorphoses, as the runaway Medea flies above Greece in the chariot her grandfather gave her, she passes over Mount Cyllene, where Menephron would incestously lie with his mother in an animal-like manner.
Hyginus in Fabulae confirms that Menephron slept with his mother, here named Blias/Bliade, and adds that he also slept with his daughter Cyllene as well.