Melrose is an unincorporated community and census-designated place in Douglas County, Oregon, United States. As of the 2020 census, Melrose had a population of 834. It was named by Henry Scott for Melrose Abbey in Scotland. Its post office, at first named Hogan, was established on May 18, 1887, and James McKinney was the first postmaster. Named earlier on as French Settlement, Oregon.