Mellisa Santokhi-Seenacherry (, ; ; born 27 October 1980) is a Surinamese lawyer, who served the First Lady of Suriname from 2020 to 2025, as the wife of Chan Santokhi.
Seenacherry studied at the Vrije Universiteit Amsterdam and the Anton de Kom University of Suriname. Seenacherry became First Lady of Suriname when her long-term partner Chan Santokhi became president on 13 July 2020 after winning the 2020 Surinamese general election.