Melkote Temple Wildlife Sanctuary is a protected area situated in the Mandya district of Karnataka, India. Established on June 17, 1974, it was primarily created to provide a refuge for the Indian wolf. The sanctuary is named after the historic Melkote pilgrimage town and its prominent temples, which border the protected zone.
The sanctuary covers an area of 49.82 square kilometres and is divided into two non-contiguous blocks Mudibetta and Narayandurga.
The terrain of the sanctuary is predominantly rocky with an elevation ranging from 800 to 1127 metres. The highest peak is Gavikallu Betta.
The sanctuary's vegetation is classified as tropical dry deciduous and scrub forest.
A botanical highlight is the presence of Cycas swamyi, a rare and endangered gymnosperm endemic to this region. Other significant flora include Sandalwood (Santalum album).