Melfi () is a town in the Guéra Region of southern-central Chad.
The Tele-Nugar Iron Mines, a UNESCO World Heritage Site, are located approximately 155 km south of Melfi.
Ethnic composition by canton in 2016:
Gogmi Canton (population: 15,917; villages: 63):
Melfi Canton (population: 23,700; villages: 104):
The town is served by Melfi Airport.