Melendugno (Salentino: or ) is a town and comune in the province of Lecce in the Apulia region of south-east Italy.
It is known for its marine, which are bathing beaches on the Adriatic Sea: Roca Vecchia, San Foca, Torre dell'Orso, and Torre Sant'Andrea, which were awarded the Blue Flag beach prize for the water quality. Melendugno also includes the of Borgagne.