Melekhovo () is a rural locality (a village) in Nikolotorzhskoye Rural Settlement, Kirillovsky District, Vologda Oblast, Russia. The population was 5 as of 2002. It is close to the IK-6 Penal Colony where Russian opposition leader Alexei Navalny is imprisoned.
Melekhovo is located 14 km east of Kirillov (the district's administrative centre) by road. Demidovo is the nearest rural locality.