Meadow Run is a long second-order tributary to Dunkard Creek in Greene County.
Meadow Run rises about 2.5 miles southeast of Kirby, Pennsylvania and then flows southeasterly to join Dunkard Creek about 1 mile southeast of Davistown, Pennsylvania.
Meadow Run drains of area, receives about 43.2 in/year of precipitation, and is about 86.1% forested.