Meadow Branch is a long 3rd order tributary to Little Creek in Sussex County, Delaware. Meadow Branch forms Little Creek along with Holly Branch.
According to the Geographic Names Information System, it has also been known historically as:
Meadow Branch rises in Delmar, Delaware and then flows northwest and north into Little Creek about 2 miles south of Laurel.
Meadow Branch drains of area, receives about 44.9 in/year of precipitation, has a topographic wetness index of 767.30 and is about 10% forested.