McQuillen is a surname of Irish origin and related to the similar family names McQuilken, McQuillan, McQuiller and McQuilling. Notable people with the surname include:
Bob McQuillen (1923âÂÂ2014), American musician and composer
Glenn McQuillen (1915âÂÂ1989), American professional baseball player
Kathleen E. McQuillen (born 1955), American, Pioneer of Open Heart Surgery Detroit Michigan