McDermott is a census-designated place in western Rush Township, Scioto County, Ohio, United States. As of the 2020 census it had a population of 308. It has a post office with the ZIP code 45652.
Platted on July 28, 1898, the community of McDermott is named after one of the area's earliest commercial ventures, McDermott Stone Company. A post office called McDermott has been in operation since 1898.
The Northwest Local School District includes the Northwest High School.