Mauléon-Barousse (; ) is a commune in the Hautes-Pyrénées department in south-western France.
Mauléon-Barousse has an oceanic climate (Köppen climate classification Cfb). The average annual temperature in Mauléon-Barousse is . The average annual rainfall is with November as the wettest month. The temperatures are highest on average in August, at around , and lowest in January, at around . The highest temperature ever recorded in Mauléon-Barousse was on 26 August 2010; the coldest temperature ever recorded was on 8 February 2012.