Matti Sarfati Harkavi (; born 13 August 1962) is an Israeli politician who currently serves as a member of the Knesset for Yesh Atid.
Sarfati Harkavi earned a BSc and PhD from the Hebrew University of Jerusalem and worked as a plant geneticist at Hazera Genetics. She became mayor of Yoav Regional Council in 2011, and was re-elected unopposed in the 2018 municipal elections.
Prior to the 2022 Knesset elections Sarfati Harkavi was placed eighteenth on the Yesh Atid list. She was elected to the Knesset as the party won 24 seats.