The is a national expressway in Ehime Prefecture, Japan. The expressway is numbered E11 between Kawanoe Junction and Matsuyama Interchange and E56 between Matsuyama and Uwajima-Kita Interchanges under the MLIT's "2016 Proposal for Realization of Expressway Numbering.
The first section of the Matsuyama Expressway to open was between Zentsuji and Mishima-Kawanoe interchanges on 16 December 1987. The final section of the expressway (16.3 km between Seiyo-Uwa and Uwajima-Kita interchanges) was opened on 10 March 2012. The route between à Âzu and à Âzu-Kitatada interchanges are officially designated as the à Âzu Road, a bypass of National Route 56. These sections are not classified as national expressways but rather as .
The entire expressway is in Ehime Prefecture. The expressway is a direct extension of the Takamatsu Expressway. Therefore, the distance and exit numbers continue from the sequence of the Takamatsu Expressway, starting at .