Kakizaki Yoshihiro, later , was the first daimyà  of Matsumae Domain in Ezo, (Hokkaidà Â), Japan.
Born on the third day of the ninth month of Tenbun 9 (1548), Yoshihiro was the third son of Kakizaki Suehiro. While the Kakizaki clan at this date exerted suzerainty over the lords of the local on the Oshima Peninsula, they were themselves subordinate to the Andà  clan of Tà Âhoku; moreover, their authority was limited to the Japanese inhabitants of the , rather than encompassing also the Ainu with whom they traded. After Toyotomi Hideyoshi defeated the Hà Âjà  at Odawara in 1590, and took measures to check the power of the great clans of the north, Yoshihiro travelled to Kyà Âto, where in the twelfth month of that year he enjoyed an audience with the kampaku at the Jurakudai palace. Reporting on the state of affairs in Ezo, Yoshiro declined a grant of five thousand koku, but had bestowed upon him Junior Fifth Court Rank, Lower Grade and the office of or Senior Vice Minister in the Ministry of Popular Affairs, thus gaining independence from the Andà Â. Receiving from Hideyoshi also three gorgeous costumes and two hundred ryà  of silver, he departed again for the north, reaching the Oshima Peninsula in the third month of 1591. Later that year, Yoshihiro sent troops to help suppress the Kunohe Rebellion, the arrows of the contingent of Ainu seeing mention in for their remarkable quality of dealing death even upon the lightly injured. In the eleventh month of the first year of Bunroku (1592), Yoshihiro travelled to à Âsaka, but Hideyoshi was at Hizen Nagoya, in relation to the invasion of Korea; reaching his camp in Kyà «shà «, as recorded in Shinra no Kiroku, on the second day of the new year Yoshihiro enjoyed another audience with Hideyoshi, where the two discussed Ezo and the invasion. Three days later, Yoshihiro had conferred upon him a affirming his rights to trade with the Ainu. In 1604 he was granted exclusive trading rights with the Ainu by shà Âgun Tokugawa Ieyasu. While neither document conferred specific territorial rights or a "fictive rice income", the Matsumae Domain would generally be treated as equivalent to tozama daimyà  with an income of ten thousand koku.
Yoshihiro built Matsumae Castle (also known as Fukuyama Castle (Fukuyama-jà  ç¦Âå±±åÂÂ).