Matelea reticulata, commonly called Pearl Milkweed Vine, Netted Milkvine, Green Milkweed Vine, Net Vein Milkvine, is a species of flowering plant in the dogbane family (Apocynaceae). It is native North America, where it is endemic to the U.S. state of Texas.
Matelea reticulata is an herbaceous perennial vine that can reach up to 12 ft in length. In the spring and summer it produces green-white, star-shaped flowers with a glistening "pearl" in the center. It fruits from May through February, producing large, spiked seed pods which open to release seeds attached to soft, silky threads.
Matelea reticulata is found in thickets on rocky hillsides. It prefers dry, sandy or rocky soil.
Matelea reticulata, like all milkweeds, is a larval host to Queen and Monarch butterflies. Milkweeds contain cardiac glycosides which the caterpillars and adult butterflies store in their bodies to deter vertebrate predators.