Matelea ecuadorensis is a species of plant in the family Apocynaceae. It is endemic to Ecuador. Its natural habitat is subtropical or tropical moist montane forests. It is threatened by habitat loss.
The species was first described as Gonolobus ecuadorensis by Rudolf Schlechter in 1906. In 1985 Gilberto N. Morillo placed the species in genus Matelea as M. ecuadorensis.