Matag-ob (IPA: ]), officially the Municipality of Matag-ob (; ; ), is a municipality in the province of Leyte, Philippines. According to the 2024 census, it has a population of 18,618 people.
In 1957 the barrios of Santo Rosario, Santa Rosa, Balagtas, San Vicente and Mabini were separated from the municipality of Palompon and constituted into Matag-ob.
Matag-ob is politically subdivided into 21 barangays. Each barangay consists of puroks and some have sitios.
In the 2024 census, the population of Matag-ob was 18,618 people, with a density of .