Massachusetts House of Representatives' 12th Hampden district in the United States is one of 160 legislative districts included in the lower house of the Massachusetts General Court. It covers part of Hampden County. Since 2007, Angelo J. Puppolo, Jr. of the Democratic Party has represented the district.
The district includes the following localities:
The current district geographic boundary overlaps with those of the Massachusetts Senate's 1st Hampden and Hampshire district and Hampden district.