Mashare is a settlement in the Kavango East Region of Namibia, just east of Rundu, the regional capital. It is the district capital of Mashare Constituency.
The settlement hosted a leprosarium until the early 1980s when the Namibian War of Independence led to its closure. The hospital accommodated thousands of patients with leprosy from Namibia, Angola, and Botswana. Until , Mashare is home to the biggest community of leprosy patients in Namibia who live together voluntarily due to their shared experience of stigma and isolation.