Masa'ud Raphael Alfasi (died 1776) was a Tunisian rabbi.
He is the author of "Mishḥa deRabuta" (Oil of Anointing), a work containing notes on all four sections of Rabbi Joseph Karo's "Shulchan Aruch" (Leghorn, 1805). He was assisted by his two learned sons, Solomon (died 1801) and Ḥayyim (died 1783), the former being the author of a similar work, "Kerub Mimshaḥ" (The Anointed Cherub), Leghorn, 1859.