Marsicano is a surname. Notable people with the surname include:
- Alberto Marsicano (1952âÂÂ2013), Brazilian musician, translator, writer, philosopher and professor
- Merle Marsicano (1903âÂÂ1983), American dancer and choreographer
- Michael Marsicano (born 1956), American entrepreneur, President and CEO of Foundation For The Carolinas
- Nicholas Marsicano (1908âÂÂ1991), American painter and university teacher
- Trevor Marsicano (born 1989), American speed skater and Olympian
- (born 1992), Italian actress