Maroantsetra is a district of Ambatosoa in Madagascar. It hosts part of Masoala National Park and part of Makira Natural Park. The district has an area of , and the estimated population in 2020 was 264,234.
The district is further divided into 20 communes:
This district is crossed by the Rantabe river, Ivoloina River, Antainambalana River, Manambolo (Est), Amaranofotsy, Mahalevona River and the Ambanizana.