Markarian 50 is a young open cluster in the Milky Way galaxy. Located at about 3,460 pc away in the constellation Cepheus, its age is estimated at only about 7.5 million years old. Markarian 50 may be a member of the OB association Cassiopeia OB2. The Wolf-Rayet star WR 157 is a member of Markarian 50.
Markarian 50 can also refer to a Seyfert galaxy in the constellation Virgo.