Mario Francesco Prezioso (born 15 April 1996) is an Italian professional footballer who plays as a central midfielder for club Giugliano.
On 30 January 2020, he moved to Serie B club Cosenza on loan.
On 26 September 2020, he joined Serie C club Modena on loan.
On 21 July 2021, he returned to Virtus Francavilla on a permanent basis and signed a two-year contract.
On 23 June 2022, Prezioso joined Ancona until June 2024.
On 22 July 2023, Prezioso moved to Potenza.
On 2 January 2024, he joined Ancona on loan.
On 17 July 2024, he joined Campobasso.