Maria Carmela Lanzetta (born 1 March 1955) is an Italian politician, who served as Minister of Regional Affairs and Autonomy from 22 February 2014 to 30 January 2015 as part of the Renzi Cabinet.
She was the mayor of Monasterace from 2006 to 2013.
Lanzetta was elected and famous for her strong anti-mafia stance, on 62.2% of the votes. She was one of three women to hold mayoral positions in this period in Calabria. In 2012, she was attacked, with a fire in her chemist shop. She soon resigned, in 2013.