Margarita Plevritou (; born 17 November 1994) is a Greek water polo player for Olympiacos. She was part of the Greek team that won the silver medal at the 2018 European Championship in Barcelona.
Her sisters, Vasiliki and Eleftheria are also water polo players.
As a professional player for Olympiacos, Plevritou has won the LEN Women's Euro League, the LEN Super Cup, the Women's LEN Trophy, and several Greek Women's Water Polo League titles.