Manolis Skoufalis (; born 21 August 1978) is a Greek coach and a former Greek footballer who last played as a midfielder for Thesprotos. He had made a name for himself in Greek football as an attacking-minded player with a flashy playing style, who usually played on the right wing.
Born in Nea Ionia, Skoufalis began playing football with Doxa Vyronas
Following his retirement from football, Skoufalis was manager in amateur division teams.In August 2025,he was appointed as assistant manager of Nikos Koustas in PAS Giannina.