Manolis Patralis (, born 6 February 1997) is a Greek professional footballer who plays as a defensive midfielder for Apollon Kalamaria of the Greek Third National Division.
On 1 July 2016 it was announced that Patralis signed a long year season contract with Aiginiakos, on loan from PAOK.
On 27 July 2017, he joined Super League Greece club Platanias on a season long-loan.
On 24 August 2018, he was loaned once again, this time to Doxa Drama.
On 16 July 2019, he joined Apollon Smyrnis on a free transfer.
On 8 July 2021, he joined AEL on a free transfer.