Makiko is a feminine Japanese given name. Notable people with the name include:
- , Japanese model, actress, writer, essayist, and lyricist
- , Japanese politician of the Liberal Democratic Party
- Makiko Furuichi (born 1987), Japanese-born French painter
- , Japanese former volleyball player
- , Japanese animator
- Makiko Hara (born 1967), Japanese independent curator
- , Japanese jazz pianist
- , Japanese former volleyball player
- , Japanese long-distance runner
- , Japanese sprinter
- , Japanese politician of the Democratic Party of Japan
- , Japanese composer
- , Japanese politician
- , Japanese actress
- , Japanese novelist
- , Japanese speed skater
- , Japanese voice actress
- , Japanese business woman and the CEO of Suntory Beverages and Food
- Makiko SaitÃ
 (born 1994), Japanese idol of idol group SKE48
- , Japanese gymnast
- , Japanese mathematician and mathematical physicist
- , Japanese politician, the daughter of former Prime Minister Kakuei Tanaka
- , Japanese rugby union and sevens player
- , Japanese actress
- , Japanese hurdler
Fictional characters
- Makiko Date, a character in the game series '
- Makiko Onimaru, a character in the manga series Muteki Kanban Musume
- Makiko Nagi, a character in the manga series Tenjho Tenge