Macho River Forest Reserve (), is a protected area in Costa Rica, managed under the Central Conservation Area, it was created in 1964 by executive decree 3417.
Part of the Ramsar site, designated in February 2003, is located within this protected area and shared with Chirripó National Park, Los Quetzales National Park, TapantàNational Park, Los Santos Forest Reserve and Vueltas Hill Biological Reserve .