] MOF-5 or IRMOF-1 is a cubic metalâÂÂorganic framework compound with the formula Zn<sub>4</sub>O(BDC)<sub>3</sub>, where BDC<sup>2âÂÂ</sup> = 1,4-benzodicarboxylate (MOF-5). It was first synthesized in the lab of Omar M. Yaghi. MOF-5 is notable for exhibiting one of the highest surface area to volume ratios among metalâÂÂorganic frameworks, at 2200 m<sup>2</sup>/cm<sup>3</sup>. Additionally, it was the first metalâÂÂorganic framework studied for hydrogen gas storage.
Yaghi's work on MOF-5 is partially responsible for his 2025 Nobel Prize in Chemistry.