The Lycoming GO-480 is a family of six-cylinder, horizontally opposed fixed-wing aircraft engines of 479.6 cubic inch (7.86 L) displacement, made by Lycoming Engines. The engine is a six-cylinder version of the four-cylinder Lycoming O-320.
GO-480 series engines are installed on a number of different aircraft types. Their main competitive engines are the Continental IO-520 and IO-550 series.
All engines have an additional prefix preceding the 480 to indicate the specific configuration of the engine. Although the series is known as the "O-480", there are only geared engines in the series. There are also numerous engine suffixes, denoting different accessories such as different manufacturers' carburetors, or different magnetos.