Lüsen (; ) is a comune (municipality) and a village in South Tyrol, located about northeast of Bolzano.
As of 30 November 2010, it had a population of 1,543 and an area of .
Lüsen (Luson) borders the following municipalities: Brixen, Mareo, Natz-Schabs, Rodeneck, St. Lorenzen, and San Martin de Tor.
The municipality of Lüsen (Luson) contains the frazioni (subdivisions, mainly villages and hamlets) Berg (Monte), Petschied (Pezzè), Rungg (Ronco) and Flitt (Valletta).
The emblem represents a knight in armor, with plumes, lance in rest on a horse facing left, both of argent on gules. The emblem, adopted in 1967, resumes an arms used by the administration of the Bishops of Brixen since 1607.
According to the 2024 census, 97.61% of the population speak German, 1.97% Italian and 0.42% Ladin as first language.