Luis Serapio del Castillo Estrada, S.J. (21 June 1935 â 4 March 2026) was a Uruguayan Roman Catholic prelate.
Luis del Castillo was ordained priest on 30 July 1966 in the Society of Jesus.
On 9 April 1988, he was appointed titular bishop of Tarasa in Numidia and auxiliary bishop of Montevideo.
He was appointed Bishop of Melo on 21 December 1999, a post he held for almost a decade. He had to resign on 13 June 2009 due to illness.
Del Castillo Estrada died on 4 March 2026, at the age of 90.