The Lowndes County School District is a public school district headquartered in Columbus, Mississippi (United States).
The district, one of two in Lowndes County, serves the towns of Caledonia, Crawford, and Artesia, the majority of the community of New Hope, small pieces of Columbus, and most rural areas in Lowndes County.
On-post families at Columbus Air Force Base have Caledonia School as one option for education of dependent children. A small piece of the Columbus AFB census-designated place is physically in the Lowndes County district.
The current headquarters building was built in 1992 as the Ecolab building. The district acquired it in 2024 as it is larger than the former district headquarters and because it is about equidistant to the three clusters of schools. The district paid $500,000 to buy it.
There were a total of 5,502 students enrolled in the Lowndes County School District during the 20062007 school year. The gender makeup of the district was 49% female and 51% male. The racial makeup of the district was 38.99% African American, 59.52% White, 0.91% Hispanic, 0.47% Asian, and 0.11% Native American. 44.0% of the district's students were eligible to receive free lunch.