Lousy Creek is a long 1st order tributary to the Reddies River in Wilkes County, North Carolina.
Lousy Creek rises about 2 miles northwest of Mulberry, North Carolina and then flows south to join the Reddies River at about 1 miles west of Fairplains.
Lousy Creek drains of area, receives about 51.6 in/year of precipitation, has a wetness index of 318.38, and is about 57% forested.