Louisiana's 5th State Senate district is one of 39 districts in the Louisiana State Senate. The district is represented by Democrat Royce Duplessis. The district was previously represented by Democrat Karen Carter Peterson from a 2010 special election to replace resigning fellow Democrat Cheryl Gray Evans until Peterson's resignation in April 2022. Diana Bajoie represented the district from 1991 to 2008. It is currently the most Democratic-leaning district in the Senate.
District 5 is primarily located in New Orleans, including parts of Carrollton, the Garden District, Mid-City New Orleans, and Uptown New Orleans, stretching to also cover a small part of Jefferson Parish.
The district overlaps with Louisiana's 1st and 2nd congressional districts, and with the 82nd, 91st, 93rd, 97th, and 98th districts of the Louisiana House of Representatives.
At 15 square miles, it is the smallest Senate district in Louisiana.
Louisiana uses a jungle primary system. If no candidate receives 50% in the first round of voting, when all candidates appear on the same ballot regardless of party, the top-two finishers advance to a runoff election.