Los Nopalitos is a census-designated place (CDP) in Webb County, Texas, United States. As of the 2020 census, Los Nopalitos had a population of 49.
Los Nopalitos is located at (27.619521, -99.205609). The CDP has a total area of , all land.
Los Nopalitos first appeared as a census designated place in the 2010 U.S. census.
Residents are in the United Independent School District. Zoned schools include: Dr. Henry Cuellar Elementary School, Antonio Gonzalez Middle School, and United South High School.
The designated community college for Webb County is Laredo Community College.