Los Lobos is a census-designated place (CDP) in Zapata County, Texas, United States. It was a new CDP for the 2010 census. As of the 2020 census, Los Lobos had a population of 7.
Los Lobos is located at (26.606536, -99.161264). The CDP has a total area of , all land.
Los Lobos first appeared as a census designated place in the 2010 U.S. census.