Loro Ciuffenna is a comune (municipality) in the Province of Arezzo in the Italian region Tuscany, located about southeast of Florence and about northwest of Arezzo.
Loro Ciuffenna borders the following municipalities: Castel Focognano, Castel San Niccolò, Castelfranco Piandiscò, Castiglion Fibocchi, Ortignano Raggiolo, Talla, and Terranuova Bracciolini. It is one of I Borghi più belli d'Italia ("The most beautiful villages of Italy").