Loreo is a comune (municipality) in the Province of Rovigo in the Italian region Veneto, located about south of Venice and about east of Rovigo. As of 31 December 2004, it had a population of 3,873 and an area of .
The municipality of Loreo contains the frazioni (subdivisions, mainly villages and hamlets) Ca'Negra, Canalvecchio, Cavanella Po, Pilastro, Retinella, Sostegno, and Tornova.
Loreo borders the following municipalities: Adria, Cavarzere, Chioggia, Porto Viro, Rosolina, Taglio di Po.