Loma Grande is a census-designated place (CDP) in Zavala County, Texas, United States. It was a new CDP formed from parts of the former Las Colonias CDP prior to the 2010 census. As of the 2020 census, Loma Grande had a population of 135.
Loma Grande is located at (28.722077, -99.832709). The CDP has a total area of , all land.
Loma Grande first appeared as a census designated place prior to 2010 U.S. census, one of two CDPs (Amaya, Loma Grande) formed out of the deleted Las Colonias CDP.